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Clinical efficacy analysis of real world percutaneous auricular vagus nerve stimulation in the treatment of non-motor symptoms of Parkinson's disease

Clinical efficacy analysis of real world percutaneous auricular vagus nerve stimulation in the treatment of non-motor symptoms of Parkinson's disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098255
Enrollment
Unknown
Registered
2025-03-05
Start date
2025-03-31
Completion date
Unknown
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's disease

Interventions

Auricular point stimulation group:Percutaneous auricular vagus nerve Stimulation (taVNS)
Simple western medicine group:An oral stable dose of an anti-Parkinson's drug

Sponsors

Lishui City Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age 45~85 years old; 2. Meet the above diagnostic criteria for Parkinson's disease and the diagnostic criteria for liver and kidney yin deficiency in TCM fibrillation disease (a. Slow movement (required); b. At least 1 of the following symptoms: muscle rigidity, resting tremor); 3. Voluntarily participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Oral and written communication barriers, unable to cooperate; 2.Patients with blood system diseases, malignant tumors, diabetic ketoacidosis or heart, liver and kidney failure, etc., whose condition is critical and difficult to evaluate effective efficacy.

Design outcomes

Primary

MeasureTime frame
Non-Motor Symptom assessment scale for Parkinson'sDisease;Parkinson’s Disease Questionnaire -39;

Secondary

MeasureTime frame
Hoehn and Yahr scale;Unified-Parkinson Disease Rating Scale ?;Constipation Assessment Scale;Pittsburgh Sleep Quality Index;Hamilton Depression Scale;Hamilton Anxiety Scale;TCM syndrome score;Quality of Life Assessment Scale (SF-36);

Countries

China

Contacts

Public ContactMimi Li

Lishui City Hospital of Traditional Chinese Medicine

1366176604@qq.com+86 198 5782 1329

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026