atelectasis
Conditions
Interventions
Group A:PEEP=0 cmH20
Group B:PEEP=4 cmH20
Group C:PEEP=12 cmH20
Sponsors
Northern Jiangsu People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with ASA classification I-II; Patients signed informed consent to participate in the study; Patients undergoing elective abdominal surgery under general anesthesia; Patients aged 18-65 years, with a BMI of 18-24 kg/m^2; Patients with an estimated operative time of >= 1.5 h and intraoperative bleeding of <= 500 ml.
Exclusion criteria
Exclusion criteria: Previous thoracic surgery; pneumothorax or alveoli on chest radiograph or CT; Pulmonary disease: chronic bronchitis, asthma, moderate-to-severe obstructive ventilatory dysfunction; Preoperative pulse oxygen saturation (SpO2) <90% on inspiratory air or SpO2 <95% on inspiratory oxygen; contraindications to pulmonary recruitment maneuvre: high intracranial Pressure, hypovolemic shock, right heart failure; Severe cardiac disease (New York Heart Association class III or IV; acute coronary syndrome or sustained ventricular tachyarrhythmia); participation in other interventional settings; and hypovolemic shock, right heart failure; severe cardiac disease (New York Heart Association, NYHA class III or IV; acute coronary syndrome or sustained ventricular tachyarrhythmia); Participation in other interventional studies or refusal to enroll.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| total time and half-time for lung compliance to return to baseline level after recruitment maneuvre; | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory mechanical parameters before and after RM, such as airway peak pressure (PIP), plateau pressure (Ppl), driving pressure (DP=Ppl-PEEP), P-V ring low inflection point, LIP return to origin time, tidal volume (VT), respiratory rate (RR); Hemodynamic indicators such as CO, SVR, SV, MAP, etc; | — |
Countries
China
Contacts
Public ContactGao Ju
Northern Jiangsu People's Hospital
Outcome results
None listed