Type 2 diabetes
Conditions
Interventions
Observation group:None
Sponsors
Wuxi People 's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Age between 18 and 70 years old. 2.Conform to the WHO 1999 diagnostic criteria for diabetes : ' three more and one less ' ( polyuria, thirsty, polydipsia, polyphagia, unexplained weight loss ) and other typical metabolic disorder syndrome, random blood glucose ( random time points within a day ) >= 11.1mmol / L ( 200mg / dl ), or fasting blood glucose ( at least 8 hours without eating ) >=7.0mmol / L ( 126mg / dl ), or 75g anhydrous glucose load 2 hours after blood glucose >=11.1mmol / L ( 200mg / dl ), the above blood glucose are venous plasma glucose. 3.Diabetic type is type 2 diabetes, and diagnosed for 3 months and above. 4.Glycosylated hemoglobin ( HbA1c ) levels were 7-9 %. 5.Patients voluntarily accept the relevant examination in the course of the study, including multiple self blood glucose monitoring ( SMBG ), dynamic blood glucose monitoring ( CGM ), biochemical test and so on. 6.No thyroid hormone replacement therapy was received or had been received but the treatment was not up to standard ; 7.Hypothyroidism and subclinical hypothyroidism are in line with the 2024 guidelines for the diagnosis and treatment of hypothyroidism : patients have obvious hypothyroidism symptoms, such as fatigue, weight gain, dry skin, etc. Laboratory tests Serum thyroid stimulating hormone
Exclusion criteria
Exclusion criteria: 1.Patients with type 1 diabetes and other special types of diabetes ; 2.Patients with obvious other endocrine diseases, such as pituitary tumors, adrenal diseases. 3.Patients with acute complications of diabetes ; complicated with infection, pregnancy, malignant tumor, mental illness. 4. Have received thyroid surgery or radiotherapy ; patients who are using drugs that affect thyroid function, such as iodide, adrenocortical hormones, and ß-receptor antagonists. 5.Severe heart disease, kidney disease or nervous system disease ; 6.Exclude patients who are using drugs that affect thyroid function, such as iodide, adrenocortical hormones, and ß-receptor antagonists. 7.Exclude serious systemic diseases, trauma and mental illness that may cause low T3 syndrome. 8.Long-term use of glucocorticoid drugs or pregnancy, lactation, trauma, acute infection and other factors affecting fasting blood glucose or insulin sensitivity. 9.Combined with other diseases that may affect blood glucose or application of drugs that may affect blood, such as pituitary disease, thyroid disease, adrenal disease, polycystic ovary syndrome, poor self ( hemoglobin male < 120gL, female <=110g / L ), blood loss and / or blood transfusion, with large doses of vitamin C or erythropoietin. 10. Patients with malnutrition or abnormal iodine intake were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood glucose; | — |
Secondary
| Measure | Time frame |
|---|---|
| Thyroid hormones; | — |
Countries
China
Contacts
Public ContactYun Hu
Wuxi People 's Hospital
Outcome results
None listed