Respiratory Failure
Conditions
Interventions
Group A :Phase 1 intervention (IntelliCycle+SIMV mode, 2 hours):
The first hour is the preparation period
The second hour was the study period, and patient data were recorded, including respiratory ra
Group B:Phase 1 intervention (SIMV mode, 2 hours):
The first hour is the preparation period
The second hour is the study period, and relevant data are recorded.
Washout period (1 hour):
Same as above,
Sponsors
Huashan Hospital, Fudan University, Shanghai, China.
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Spontaneously breathing mechanically ventilated patients undergoing endotracheal intubation or tracheostomy; 2. The oxygenation index is 150-300mmHg; 3. 18 years old< = age<80 years old, regardless of gender; 4. 18kg/m^2<=BMI<=30 kg/m^2; 5. Patients or their families will fully understand the purpose and significance of the trial, voluntarily participate and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients who will be sedated in the general ward for > 3 days before being transferred to the ICU or in the ICU before signing the informed consent form; 2. Have a history or evidence that they are at increased risk during sedation/anesthesia during the screening period; 3. Pregnant and lactating women; 4. Patients with hypoxemia caused by pulmonary embolism, pneumothorax, airway obstruction, etc 5. Patients with hemodynamic disorders, patients with myocardial ischemia, intracranial hypertension, malignant tumors, and tuberculosis 6. Participated in other clinical trials within 1 month before screening. 7. The investigators decide that the patient is not eligible for inclusion in the clinical trial for a variety of reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Work of breath; | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory Rate;Heart Rate; | — |
Countries
China
Contacts
Public ContactFeng Zhao, Weijia Li
Huashan Hospital, Fudan University, Shanghai, China.
Outcome results
None listed