Non-functional pituitary adenoma
Conditions
Interventions
Observation group:None
Sponsors
Affiliated Hospital of Guangdong Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Brain magnetic resonance imaging (MRI) plain scan plus contrast enhancement examination suggested pituitary adenoma. 2.It was completely resected for the first time through endoscopic endonasal transsphenoidal surgery, and was pathologically confirmed as non-functional pituitary adenoma. 3.Aged between 18 and 60 years old, clinically diagnosed as non-functional pituitary adenoma. 4.Non-contact intraocular pressure <= 21 mmHg (1 mmHg = 0.133 kPa). 5.There was no previous history of intracranial diseases and trauma, no history of intracranial surgery;no history of ocular trauma, no glaucoma, no optic nerve and retinal diseases, and no history of intraocular surgery. 6.Previous refractive error < ±6.0D (spherical lens) and < 3.00D (cylindrical lens). 7.The images of OCT and OCTA were clear, and the imaging quality of DTI was good.
Exclusion criteria
Exclusion criteria: 1.There was a previous history of intracranial diseases and trauma, a history of intracranial surgery, a history of ocular trauma, glaucoma, optic nerve and retinal diseases, and a history of intraocular surgery. 2.Previous refractive error was > ±6.0D (spherical lens) and > 3.00D (cylindrical lens). 3.The images of OCT and OCTA were unclear, and the imaging quality of DTI was poor. 4.Those who were unable to obtain the area of the region of interest due to the thinning of the optic chiasm caused by compression.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Best corrected visual acuity;Mean deviation (MD) value of visual field;Optic disc and macular OCT parameters, paraoptic disc and macular OCTA parameters;Each segment of the visual pathway includes the optic nerve, optic chiasm, optic tract, and optic radiation, as well as the FA value and ADC value; | — |
Secondary
| Measure | Time frame |
|---|---|
| The diameters of the tumor shown by magnetic resonance imaging (MRI); | — |
Countries
China
Contacts
Public ContactYanhua Pang
Affiliated Hospital of Guangdong Medical University
Outcome results
None listed