Elder breast cancer with lymph node metastasis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Sign written informed consent; 2. Female, age >= 65 years; 3. Breast cancer patients who have undergone radical surgery for breast cancer (radical surgery refers to: modified radical mastectomy, radical mastectomy or simple mastectomy + axillary lymph node dissection), and postoperative histology confirmed with axillary lymph node metastasis; 4. Postoperative immunohistochemical typing and pTNM staging are consistent with: - (1) Patients with Luminal type A (ER and PR positive with a positivity rate of >= 20%, Her2 gene negative, Ki67 = 20%, Ki67 = 70 years, Luminal B, Her2 geno-negative type, and meet ER and PR positivity with a positivity rate of >= 20%, Ki67 = 70 years, but who refuse or are unable to tolerate chemotherapy treatment with a positive ER or PR with a TNM stage of pTanyNanyM0; 5. ECOG score of 0 - 1 point; 6. The expected survival time is > 6 months.
Exclusion criteria
Exclusion criteria: 1.Patients who have received preoperative neoadjuvant therapy in the past; 2.Patients with bilateral breast cancer; 3.Patients whose paraffin tissue specimens have been stored for more than 3 years at the start of the project; 4.Patients with mental disorders who are unable to cooperate with subsequent treatment and follow-up; 5.Patients with a history or evidence of disease, treatment or abnormal laboratory test values that may interfere with the trial results or prevent full participation in the study, or other situations deemed unsuitable for inclusion by the investigator, or those considered to have other potential risks and thus not suitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival rate; | — |
Countries
China
Contacts
Qilu Hospital of Shandong University