Genitourinary Syndrome of Menopause
Conditions
Interventions
Radiofrequency Group:AI-controlled Thermal Radiofrequency Therapy Device
Estriol Group:Estriol Cream
Blank control group:No intervention measures applied
Sponsors
West China Second Hospital of Sichuan University
Eligibility
Sex/Gender
Female
Age
45 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria (must meet all of the following criteria): 1.Voluntarily participate in the study and sign the informed consent form; 2.Female participants aged 45-60 years post-menopause; 3.Meet at least one of the following three indications: 1) Vaginal dryness, burning, and irritation symptoms; 2) Sexual symptoms such as lack of lubrication, discomfort or pain, or functional impairment; 3) Urinary symptoms such as urgency, dysuria, and recurrent chronic urinary tract infections, excluding acute urinary tract infections; or experience symptoms of stress urinary incontinence.
Exclusion criteria
Exclusion criteria: Exclusion Criteria: 1.Pregnant women or those with recent fertility intentions; 2.History of photosensitivity; 3.Severe systemic medical conditions that affect daily life (e.g., severe cardiovascular diseases, immune system disorders); 4.Co-existing blood disorders, immune dysfunction, or oncological diseases; 5.History of gynecological surgery (e.g., mesh implantation); 6.Abnormal findings from TCT, ultrasound, infection screening tests, or vaginal smear; 7.Patients with psychological or mental disorders such as depression, who are unable to complete follow-up; 8.Severe hormone-related diseases or those at high risk for breast cancer or endometrial cancer; 9.Participants with known contraindications to estrogen therapy. (Note: Only patients who answer "No" to all of the above items will be eligible for inclusion.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CVFSFI,Chinese version of the female sexual function scale;Vaginal resting pressure and maximum contraction pressure;Pad test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Urinary Incontinence Questionnaire (Short Form); | — |
Countries
China
Contacts
Public ContactWei Dongmei
West China Second University Hospital, Sichuan University
Outcome results
None listed