Unilateral primary invasive breast cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.A patient with unilateral primary invasive breast cancer diagnosed by histopathology, excluding ocessive breast cancer, inflammatory breast cancer and eczema-like cancer; 2.Operable patients with no distant metastases at diagnosis (stage T1-T3, any N, M0); 3.After diagnosis, the patient was initiated with endocrine therapy and regular GnRHa between January 1, 2013 and December 31, 2023;
Exclusion criteria
Exclusion criteria: 1.Stage IV (metastatic) breast cancer was diagnosed; 2.The patient had undergone bilateral ovariectomy or ovarian radiotherapy before first GnRHa treatment; 3.The patient had not been treated with GnRHa drug castration since diagnosis; 4.The patient was postmenopausal at first diagnosis (no menstruation in the past 12 months or menopausal hormone levels at diagnosis, E2 30U/L); 5.The investigator determined that the patient had any other condition that made her unfit to participate in the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Estradiol; | — |
Secondary
| Measure | Time frame |
|---|---|
| Follicle Stimulating Hormone;Luteinizing Hormone;Anti-Mullerian Hormone;Menstruation; | — |
Countries
China
Contacts
Sun Yat-sen Memorial Hospital, Sun Yat-sen University