Infertility
Conditions
Interventions
HRT group:NA
Sponsors
Chongqing Health Center for Women and Children
Eligibility
Sex/Gender
Female
Age
18 Years to 38 Years
Inclusion criteria
Inclusion criteria: 1. Women aged =8 mm on endometrium transformation day 4. Have received estradiol valerate for no more than 21 days 5. Planned SET (single embryo transfer) with 1 good quality blastocyst for transfer (4BB and above)
Exclusion criteria
Exclusion criteria: 1. >= 2 previously failed cycles of ET 2. History of recurrent miscarriages (>= 2 times of miscarriages) 3. Severe endometriosis (Endometriosis American Society for Reproductive Medicine [ASRM] criteria from 1996) 4. Hydrosalpinx 5. Diagnosis of uterine abnormalities including malformed uterus (uterus unicornis, septate uterus, endometrial polyp, or duplex uterus), submucous myoma, or intrauterine adhesion 6. Basal FSH > 10 IU/L before controlled ovarian stimulation (COS) 7. Pre-implantation genetic testing for aneuploidy, monogenic disorders or structural re-arrangements 8. No good blastocyst to be transferred 9. Untreated or uncured endocrine and metabolic disorders (such as pituitary disease, thyroid disease, or adrenal disease) or other comorbidities that may affect study endpoints, such as diabetes mellitus, as judged by investigator 10. Patients with any diseases that cannot tolerate embryo transfer or pregnancy 11. Patients used drugs that may affect the effectiveness and safety evaluation of the study, such as systemic hormonal medications (thyroid hormone replacement therapy exclusive) 12. Simultaneous participation in another clinical study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum Progesterone Levels on The Day of ET; | — |
Secondary
| Measure | Time frame |
|---|---|
| hCG Test;Clinical Pregnancy;Early Miscarriage;Ongoing Pregnancy Rate;Adverse Event; | — |
Countries
China
Contacts
Public ContactHong Ye
Chongqing Health Center for Women and Children
Outcome results
None listed