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Correlation between blood pressure variability and early neurological deterioration in patients with branch atheromatous disease

Correlation between blood pressure variability and early neurological deterioration in patients with branch atheromatous disease

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500098160
Enrollment
Unknown
Registered
2025-03-04
Start date
2022-04-28
Completion date
Unknown
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Branch atheromatous disease

Interventions

END(Early neurological deterioration) Group:None
Non-END Group:None

Sponsors

Aerospace Central Hospital, No. 15, Yuquan Street,Haidian District, Beijing, China.
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients met the diagnostic criteria of BAD in the Chinese Expert Consensus on Branch Atheromatous Disease (2021) published by the Small cerebral Vascular Disease Branch of the Chinese Stroke Society , and the onset of BAD was less than 24 hours; 2. Cerebral hemorrhage and other intracranial diseases confirmed by CT or MRI were excluded; 3. Patients and their families had given informed consent and the clinical data were complete.

Exclusion criteria

Exclusion criteria: 1.Imaging indicated that the responsible large vessel stenosis was >= 50%; 2.Imaging showed that there are unstable plaques in intracranial large arteries, external carotid artery and vertebral artery, that can cause arterio-arterial embolism; 3.DWI series showed cortical infarcts, watershed infarcts and multiple cerebral infarcts; 4.Cerebral infarcts caused by other clear etiological factors, such as immune or infectious vasculitis, cardiogenic cerebral embolism, etc. 5.Patients with tumors, severe cardiopulmonary, hepatic and renal dysfunction or end-stage diseases; 6.Those who cannot cooperate with clinical diagnosis and treatment, have not signed informed consent or have poor compliance.

Design outcomes

Primary

MeasureTime frame
Blood pressure variability parameters;

Secondary

MeasureTime frame
White blood cell count;Neutrophil count;Fasting blood-glucose;Triglyceride;Total cholesterol;Low density lipoprotein cholesterin;Uric acid;Homocysteine;D-dimer;Infarction location;

Countries

China

Contacts

Public Contactzhuhui

Aerospace Central Hospital

beiyiky2012@126.com+86 136 4107 9101

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026