Cervical spondylosis
Conditions
Interventions
Propofol group:Propofol was used to induce 2 mg/kg, plasma targeted continuous intravenous infusion of remifentanil (3.0-5.0 ng/ml), and propofol was used to pump at a constant rate, with an initial d
Ciprofol group:0.4 mg/kg was induced with cyclopofol, plasma targeted continuous intravenous infusion of remifentanil (3.0-5.0 ng/ml), and cyclopofol was used to pump at a constant rate, with an initi
Sponsors
The First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing anterior cervical decompression and fusion for the first time; 2. Age 18-70 years old; 3. ASA Grade I~III.; 4. BMI 15~28 kg/m^2 ; 5. Able to understand this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with cervical vertebra fracture caused by trauma; 2. the presence of a difficult airway in the preoperative assessment; 3. Patients who are allergic to anesthetic drugs such as cyclopofol and propofol; 4. Patients who have been taking sedative and anti-anxiety drugs for a long time; 5. Severe cardiovascular and cerebrovascular diseases or psychiatric diseases in the past; 6. Severe liver and kidney insufficiency; 7. Patient or family member refuses to participate in this study; 8. Patients participating in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative recovery quality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure;Heart rate;Intraoperative anaesthetic drug use;Extubation time;Duration of anaesthesia;Length of stay in the Postanesthesia care unit;Incidence of adverse events;Postoperative delirium;Postoperative sleep quality;Length of hospital stay;Postoperative complications;Duration of surgery; | — |
Countries
China
Contacts
Public ContactJu Li
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed