Hypertrophy of the tonsils accompanied by adenoid hypertrophy
Conditions
Interventions
Remimazolam group (R):Remimazolam tosilate 0.1mg/kg was administered at the end of operation
Propofol group (P):Propofol 1mg/kg was administered at the end of surgery
Sponsors
Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
All
Age
3 Years to 7 Years
Inclusion criteria
Inclusion criteria: 1. Age: 3-7 years old 2. American Society of Anesthesiologists (ASA) grade ? or ?; 3. Patients undergoing elective tonsillectomy or adenoidectomy;
Exclusion criteria
Exclusion criteria: 1. Children with liver and kidney dysfunction, cardiovascular dysfunction, endocrine dysfunction, or other organ dysfunction (ASA Class III or IV) 2. Allergy or hypersensitivity to remimazolam; 3. Mental disorders; 4. Recent respiratory tract infection (2 weeks); 5. Other reasons for not participating in the trial in the opinion of the investigator: being in professional care or living in a social welfare institution or any other factors that may affect their ability to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of delirium during the recovery period; | — |
Secondary
| Measure | Time frame |
|---|---|
| FLACC Scale;Post-hospital Behavior questionnaire;Anesthesia recovery indicators;Modified Aldrete Score;Duration of surgery;Duration of anesthesia;Time to extubation;Time to recovery;Incidence of rescue propofol or fentanyl in PACU;Systolic Blood Pressure;Diastolic blood pressure;Mean arterial pressure;Heartrate;The occurrence of adverse events within 48 h postoperatively;Parents' satisfaction (Numerical scoring method); | — |
Countries
China
Contacts
Public ContactYong Pang
Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed