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Does Needle Approach Matter in Two-Point Thoracic Paravertebral Block? A Comparative Study on Analgesic Outcomes

Clinical study of the analgesic effect of thoracic paravertebral nerve block with different approaches in two-point method

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098103
Enrollment
Unknown
Registered
2025-03-03
Start date
2025-03-07
Completion date
Unknown
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Analgesia

Interventions

Out-of-plane approach group:TPVB was performed via the out-of-plane approach at T3/T4 and T6/T7, injecting 15 mL of 0.33% ropivacaine per site
In-plane approach group:TPVB was performed via the in-plane approach at T3/T4 and T6/T7, injecting 15 mL of 0.33% ropivacaine per site

Sponsors

The Second Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists (ASA) grade I-III; 2. Age 18-60 years old; 3. Body mass index (BMI) of 18.5-23.9 kg/m^2; 4. Elective single-port thoracoscopic lobectomy under general anesthesia is planned.

Exclusion criteria

Exclusion criteria: 1. Diagnosed mental illness; 2. Inability to communicate due to cognitive impairment or language impairment before surgery; 3. History of chronic pain or opioid abuse before surgery; 4. History of drug abuse or alcohol abuse in the past 3 months; 5. Those who have infection at the puncture site or have been infected before surgery; 6. Accompanied by blood diseases, coagulation dysfunction and other serious comorbidities; 7. Those who have an allergic reaction to the drugs used in this study; 8. Patients with severe scoliosis or a history of thoracotomy surgery.

Design outcomes

Primary

MeasureTime frame
The area under the curve (AUC) of Visual Analog Scale (VAS) scores at rest ;The area under the curve (AUC) of the Visual Analogue Scale (VAS) during exercise ;

Secondary

MeasureTime frame
Duration of Analgesia;Onset time of sensory blockade;Time to stabilization of block level;Number of blocked dermatomal segments (T);Nerve block procedure time;Pain Assessment during Invasive Procedures;Hemodynamics;Patient Satisfaction Score;

Countries

China

Contacts

Public ContactXin Zhao

The Second Hospital of Shandong University

lujnzx@sohu.com+86 176 6008 5551

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026