Epilepsy
Conditions
Interventions
Intervention group:After the patient has a habitual seizure, the characteristic signal is automatically recognized, and all electrode contacts in the target area (calculated for each patient) are elec
Sponsors
The Second Affiliated Hospital of the Army Medical University
Eligibility
Sex/Gender
All
Age
12 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for drug-refractory epilepsy; 2. Aged between 12-65 years old, male or female; 3. Have undergone preoperative evaluation of the multidisciplinary system, and SEEG monitoring will be carried out according to the needs of diagnosis and treatment; 4. Frequency of seizures in the past 3 months>=1 time/week, with/without secondary seizures; 5. After being informed of the current treatment options and potential risks, the patient agrees to participate in this study and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients with secondary epilepsy caused by cerebrovascular diseases, tumors, infections, or autoimmune diseases. 2.Serious heart, liver, kidney physical diseases or severe or progressive neurological and psychiatric diseases with severe arrhythmia, QTc>450ms; transaminase exceeding the upper limit of normal values (0-40U/L) by three times, total bilirubin (3.4-17.1 µ mol/L), creatinine (44-133umol/L) exceeding the upper limit of normal values by 1.5 times, or creatinine clearance rate<45ml/min.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Seizure rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Stereoelectroencephalographic changes; | — |
Countries
China
Contacts
Public ContactZhang Chunqing
The Second Affiliated Hospital of the Army Medical University
Outcome results
None listed