Central lung cancer
Conditions
Interventions
Image-enhanced endoscopy:Performing bronchoscopic biopsy forceps biopsy under image enhanced endoscopy
White light endoscopy group:Perform bronchoscopic biopsy forceps biopsy under normal white light
Sponsors
Shanghai Changhai Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-80 years old; 2. the presence of tracheobronchial intraluminal lesions or central airway involvement of central lung type lesions on chest CT, and indications of the need for bronchial intraluminal biopsy forceps biopsy for definitive diagnosis; 3. the patient volunteers to undergo bronchoscopy and has no contraindications to bronchoscopy; 4. the subject (or his/her guardian) was able to understand the purpose of the trial, agreed to participate in the study and signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1. with severe cardiac or pulmonary disease, coagulation disorders, allergy to anesthetics, or other conditions that do not tolerate bronchoscopy; 2. the lesion is located in the periphery of the lung and is not visible on conventional bronchoscopy; 3. the lesion does not infiltrate the bronchial mucosa and only needle aspiration biopsy is used; 4. preoperative imaging assessment suggests that the lesion is highly vascularized and that severe hemorrhage may result from endobronchial biopsy forceps biopsy; 5. Tracheobronchial lesions causing moderate to severe stenosis of the trachea requiring concomitant therapeutic bronchoscopic manipulation, such as high-frequency loop, high-frequency electrocoagulation, cryotherapy, and balloon dilatation; 6. patients who have been definitively diagnosed with granulation tissue growth after airway stent or pneumatic cannula placement; 7. taking anticoagulant or antiplatelet aggregation drugs, or bleeding tendency that cannot be improved; 8. patients who cannot cooperate with the doctor to complete the bronchoscopy, such as patients with psycho-neurological diseases, intellectual disabilities, psychological disorders, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Operation time of flexible bronchoscopy biopsy;Bleeding volume during flexible bronchoscopy biopsy;Sample quality of flexible bronchoscopy biopsy;Incidence of complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative psychological pressure of the operator;Visual field visibility score under the microscope;Color difference between bleeding point and surrounding mucosa/blood;Diagnostic rate; | — |
Countries
China
Contacts
Public ContactHaidong Huang
Shanghai Changhai Hospital
Outcome results
None listed