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Observation on the effect of different doses of remazolam combined with bupropion in the treatment of early abortion in pregnancy

Observation on the effect of different doses of remazolam combined with bupropion in the treatment of early abortion in pregnancy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098090
Enrollment
Unknown
Registered
2025-03-03
Start date
2025-04-30
Completion date
Unknown
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early pregnancy

Interventions

A Group:0.15mg/kg Methylphenidate-Rimazolam for Injection
B Group:0.2mg/kg Methylphenidate-Rimazolam for Injection

Sponsors

Sichuan Province Science City Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 49 Years

Inclusion criteria

Inclusion criteria: 1.undergoing elective abortion; 2.American Society of Anesthesiologists (ASA) I or II; 3.clinically confirmed pregnancy (<12 weeks) by color Doppler ultrasound; 4. 18 ~ 49 years of age; 5.body mass index (BMI) between 18 - 30 kg/m2, no cervical related diseases, no previous cervical surgery.

Exclusion criteria

Exclusion criteria: 1. refusal to participate; 2. ASA Class III or above; 3. hypersensitivity to remazolam or bupropion; 4.severe hepatic/renal/cardiorespiratory/central nervous system dysfunction; 5. duration of a single procedure >10 minutes; 6.and prolonged use of sedative or analgesic medications.

Design outcomes

Primary

MeasureTime frame
Propofol dosage;Patient response during cervical dilation;

Secondary

MeasureTime frame
Remazolam dose;Postoperative recovery time of patients;

Countries

China

Contacts

Public ContactYulong Zhong

Sichuan Province Science City Hospital

zhongyulong1988@163.com+86 187 8041 6982

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026