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Study on the Effect of Bupivacaine Liposome Injection on Postoperative Pain and Oxidative Stress in Patients Undergoing Intercostal Nerve Block During Video-assisted Thoracoscopic Wedge Resection of the Lung

Study on the Effect of Bupivacaine Liposome Injection on Postoperative Pain and Oxidative Stress in Patients Undergoing Intercostal Nerve Block During Video-assisted Thoracoscopic Wedge Resection of the Lung

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098077
Enrollment
Unknown
Registered
2025-03-03
Start date
2025-03-03
Completion date
Unknown
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulmonary nodule

Interventions

Bupivacaine Liposome Group:After the resection of the lung specimen, the surgeon administers bupivacaine liposome injection for intercostal nerve block under thoracoscopy.
Ropivacaine group:After the removal of lung specimens, the surgeon administered ropivacaine injection for intercostal nerve block under thoracoscopy

Sponsors

Chengdu Jinniu District People’s hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients with ASA physical status classification of I-II; 2. Patients scheduled for elective thoracoscopic lung resection under general anesthesia with bronchial intubation.

Exclusion criteria

Exclusion criteria: 1. ASA class III or above; 2. Trauma and emergency patients; 3. New York Heart Association (NYHA) functional class 3-4; 4. Body Mass Index (BMI) > 35 kg/m²; 5. Diabetes mellitus requiring insulin therapy; 6. Renal system diseases; 7. Hepatic system diseases.

Design outcomes

Primary

MeasureTime frame
IL-6;C-reactive protein;TNF-a;Numeric Rating Scale (NRS) score;

Secondary

MeasureTime frame
Adverse reactions;

Countries

China

Contacts

Public ContactRun Wang

Chengdu Jinniu District People’s hospital

406265632@qq.com+86 130 3282 9403

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026