Catheter-Related Bladder Discomfort
Conditions
Interventions
SK group:Escitalopram 0.5 mg/kg, diluted to 10 ml, was slowly injected into the bladder through a urinary catheter, which was clamped shut for 20 min and then opened.
NSgroup:Saline 10 ml was slowly injected into the bladder via catheter.
Sponsors
Xiangyang No.1 People’s Hospital Hubei University of Medicine
Eligibility
Sex/Gender
Male
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. ASA grade 1 to 3; 2. Preoperative urinary catheterization is required; 3. Male 18 to 60 years of age; 4. BMI < 27.
Exclusion criteria
Exclusion criteria: 1. Allergy or contraindication to the test drug; 2. history of chronic pain; 3. long-term use of analgesic or psychotropic medications; 4. severe hepatic or renal dysfunction; 5. inability to cooperate with the evaluation; 6. intracranial hypertension; 7. severe hypertension (SBP >160 mmHg); 8. difficulty in catheter placement; 9. bladder outflow tract obstruction; 10. neurogenic bladder; 11. Parkinson's disease; 12. Diabetes mellitus; 13. OAB (more than 3 nocturnal urinations or more than 8 urinations in a 24-hour period); transurethral resection of the prostate for benign prostatic hyperplasia; 14. end-stage renal disease (urine output of less than 50 ml per 24 hours); or urinary tract infections.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and severity of postoperative CRBD; | — |
Secondary
| Measure | Time frame |
|---|---|
| sedation level; | — |
Countries
China
Contacts
Public ContactGong Ting
Xiangyang No.1 People’s Hospital Hubei University of Medicine
Outcome results
None listed