Helicobacter pylori infection
Conditions
Interventions
Group A:Minocyclin (100mg each time, bid day)+Captagon (20 mg each time, qd) for 14 days.
Group B:Minocyclin(100mg each time, bid day)+Vonoprazan (20 mg each time, bid) for 14 days.
Sponsors
Fujian Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Adult patients, aged 18 to 80 years; 2. Helicobacter pylori was not eradicated with tetracycline, minocycline or doxycycline before treatment. Antibiotics, bismuth and Chinese medicine were not taken for 4 weeks before treatment, and PPI, H2 receptor antagonist and other drugs were not taken for 2 weeks; 3. Hp-positive was diagnosed by C13 or C14-urea breath test and rapid urease test; 4. Informed and agreed to participate in the study, patients with complete medical records and follow-up records.
Exclusion criteria
Exclusion criteria: 1. With severe heart, lung, and kidney dysfunction and low immunity; 2. Patients with drug allergy contraindications; 3. Persons with mental illness or communication difficulties; 4. Pregnancy, lactation; 5. Patients with organic diseases such as gastrointestinal tumor and gastrointestinal hemorrhage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Degree of clinical symptom remission;Adverse reaction; | — |
Countries
China
Contacts
Public ContactXueping Huang
Fujian Provincial Hospital
Outcome results
None listed