postoperative pulmonary complications
Conditions
Interventions
control group:Before removing the endotracheal tube, the lung hyperinflation are preformed 8 to 10 times with pure oxygen (FiO2 100%) through an anesthesia machine
exprimental group:Before removing the endotracheal tube, the lung hyperinflation are preformed 8 to 10 times with air (FiO2 21%) through a manual resuscitator
Sponsors
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: patients >= 18 years of age, ASA classification I - III, elective abdominal surgery, expected operative time > 2 hours, planned extubation in the operating room.
Exclusion criteria
Exclusion criteria: age 30 kg/m^2 pregnant or breastfeeding; diagnosis or suspicion of intracranial hypertension, psychiatric disorders, cognitive dysfunction; patients with apnea syndrome and suspected difficult airway; mechanical ventilation (including CPAP) within the last 15 days, pneumothorax or large buboes, COPD requiring oxygen or CPAP, history of acute lung injury or acute respiratory distress syndrome within the last 3 months; severe coronary artery disease, NYHA cardiac function class III - IV, right heart failure; severe liver disease (e.g., liver failure); chronic liver disease (e.g., hepatic failure) history of acute lung injury or acute respiratory distress syndrome within the last 3 months; severe coronary artery disease, NYHA cardiac function class III - IV, right heart failure; severe liver disease (e.g., hepatic failure); chronic renal failure (glomerular filtration rate < 30 ml/min /1.73 m^2); and patients consenting to other interventional trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative atelectasis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxygenation index;Hypoxemia associated with hyperinflation ;Bradycardia associated with hyperinflation ;hypotension associated with hyperinflation ;use of Vasoactive drug;Postoperative respiratory tract infection;Postoperative respiratory failure;Postoperative pleural effusion;Postoperative nausea and vomiting;Postoperative pain;Postoperative non-planed transferred to ICU;Length of Hospital Stay;Postoperative mortality; | — |
Countries
China
Contacts
Public ContactQiang Lyu
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
Outcome results
None listed