Kashin-Beck Disease
Conditions
Interventions
Sponsors
Department of Orthopedics, West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: After review and approval by the Medical Ethics Committee of West China Hospital of Sichuan University, patients with advanced knee and ankle osteoarthritis who meet the inclusion criteria and are accurately diagnosed by multi-radiomics and have failed to respond to conservative treatment are prospectively included and require joint replacement. 1) Unilateral total knee or ankle reconstruction under general anesthesia; 2) Patient/family member is informed and signs the informed consent form and is willing to participate in the study; 3) The preoperative American Society of Anesthesiologists classification (anesthesia risk assessment) is grade I-II.
Exclusion criteria
Exclusion criteria: 1) Those who cannot cooperate for various reasons; 2) Those who suffer from chronic pain or take analgesic drugs for a long time; 3) Patients with deep vein thrombosis of the affected limb, atherosclerotic plaque of the lower limb, and reduced arterial elasticity before surgery; 4) infection and revision; 5) Severe sleep disturbance or anxiety disorder (PSQI> 7 points); 6) Those who are allergic to or have adverse reactions to conventional analgesic drugs after surgery; 7) Patients with impaired renal or hepatic function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain Visual Analog Scale;Joint mobility;12-Item Short Health Survey Score;American Knee Society Score (AKS);Functional Scoring for Adult Osteoarthropathy in Tibetan Areas; | — |
Secondary
| Measure | Time frame |
|---|---|
| Surgery time;Hospital Stay;Patient Satisfaction;30-day readmission; | — |
Countries
China
Contacts
Public ContactZongke Zhou
West China School of Medicine and West China Hospital, Sichuan University
Outcome results
None listed