depression
Conditions
Interventions
MST group:The MST group received MST treatment three times a week for 4 weeks on the basis of routine antidepressant drug treatment.
MECT group:The MECT group received MST treatment three times a week for 4 weeks on the basis of routine antidepressant drug treatment.
control group:conventional drug therapy/treatment
Sponsors
Shandong Mental Health Center
Eligibility
Sex/Gender
All
Age
13 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1) Inpatients of a specialized hospital in Shandong Province, aged 13 - 18 years old; 2) Voluntarily consent to receive treatment and research procedures; 3) Meet the diagnostic criteria for major depressive disorder in ICD - 11; 4) Meet the criteria for treatment - resistant depression, with no symptom improvement after adequate dosage and full - course treatment with two or more antidepressants; 5) Baseline CDI score >= 19 (for those aged 13 - 17) or HAMD - 17 >= 17 (for those over 17); 6) Be suitable for convulsive treatment; 7) Agree to maintain their current antidepressant treatment interventions; 8) Have no auditory or visual impairment and be able to cooperate in completing the assessment during the interview.
Exclusion criteria
Exclusion criteria: 1.Severe organic brain diseases, such as epilepsy, cerebral hemorrhage, dementia; 2.Complicated with severe somatic diseases, such as cardiovascular diseases, liver and kidney diseases, etc; 3.Patients with contraindications to MECT or MST treatment; 4.Taking benzodiazepine drugs at a dose greater than 2 mg/day of lorazepam or equivalent dose, or any anticonvulsant drugs; 5.Unable to communicate fluently in language to complete neuropsychological tests.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Children's Depression Inventory;Beck Depression Inventory ;Hamilton Depression Rating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment (MoCA) form;Global Impression Scale (CGI); | — |
Countries
China
Contacts
Public ContactWang Wei
Shandong Mental Health Center
Outcome results
None listed