Overactive bladder- dry
Conditions
Interventions
Group B:Standard behavioral therapy combined with short-term high dose exogenous vitamin D supplementation
Group A:Standard behavioral therapy combined with solinasine
Sponsors
Children's Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
5 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Children older than 5 years who were diagnosed with dry OAB at the Department of Urology, Children's Hospital Affiliated to Chongqing Medical University. 2.The results of our laboratory indicated that the serum vitamin D level was lower than 35ng/mL. 3.The child (guardian) has been informed of the nature of the study, understands the protocol, is able to guarantee compliance, and signs informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients with other urinary system malformations or serious diseases (such as hypospadias, cryptorchidism, posterior urethral valvular disease, vesicoureteral reflux, neurogenic bladder, urinary system tumors, urinary calculi, bladder and urethral injuries, etc.); 2.Associated with neurological disorders (e.g. epilepsy, spinal cord injury, dysplasia of spinal cord, tethered cord syndrome, multiple sclerosis, autism spectrum disorder, etc.); 3.Patients with severe heart disease, abnormal liver and kidney function, lung disease, bone malformation, severe digestive tract disease, genetic metabolic disease; 4.Patients with a history of gastrointestinal surgery and urinary system surgery; 5.Patients with dry stool and long-term constipation; 6.Patients who are taking anticonvulsant and antiepileptic drugs, hormones, and antituberculosis drugs; 7.Patients with previous history of hypercalcemia, hyperphosphatemia and renal rickets; 8.History of unexplained hematuria and urinary tract infection in the last 1 year; 9.Patients with a history of allergy or allergic disease to vitamin D preparations; 10.Those who had participated in another clinical study at the time of visit or were during follow-up of another clinical study; 11.Those who did not want to participate in the study or had poor follow-up compliance;
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Urgent urination scores after 6 and 12 weeks of intervention; | — |
Primary
| Measure | Time frame |
|---|---|
| The number of daily reductions in the frequency of urination after 12 weeks of intervention; | — |
Countries
China
Contacts
Public ContactXing Liu
Children's Hospital of Chongqing Medical University
Outcome results
None listed