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Effect of physical activity on chemotherapy-induced peripheral neuropathy in elderly patients with colorectal cancer

Effect of physical activity on chemotherapy-induced peripheral neuropathy in elderly patients with colorectal cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098011
Enrollment
Unknown
Registered
2025-02-28
Start date
2025-03-01
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chemotherapy-induced peripheral neuropathy

Interventions

Experimental group:Exercise intervention
Control group:Routine movement management

Sponsors

Affiliated Hospital of Jiangnan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Diagnosed with colorectal cancer through pathological diagnosis; 2. Age>=60 years; 3. Initial use of oxaliplatin with or without other chemotherapy drugs, and continuous use of this regimen for the next 4 courses of chemotherapy; 4. ECOG PS score 0-2 points.

Exclusion criteria

Exclusion criteria: 1. Suffering from other neurological diseases at the same time, such as peripheral neuropathy caused by diabetes, herpes zoster, and faculty Systemic lupus erythematosus, etc.; 2. At the same time, it is accompanied by severe heart, liver and kidney insufficiency; 3. At the same time, it is accompanied by other diseases that affect balance function or gait, such as fractures, trauma, etc.; 4. At the same time, it is accompanied by hearing impairment, aphasia and other diseases, dementia, mental disorder and cognitive impairment; 5. Reluctance to participate in surveys.

Design outcomes

Primary

MeasureTime frame
Incidence of chemotherapy-induced peripheral neuropathy;CIPNAT;IPAO-L;EORTC QLQC30;

Secondary

MeasureTime frame
BBS;MFES;

Countries

China

Contacts

Public ContactChen Ying

Affiliated Hospital of Jiangnan University

chenying126073@126.com+86 510 68089813

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026