Short stature
Conditions
Interventions
intervention group:Taking GABA granules ("Becco future ?”), Take 1 bag of milk daily before going to bed for 6 months.
Sponsors
children's hospital of fudan university
Eligibility
Sex/Gender
All
Age
4 Years to 11 Years
Inclusion criteria
Inclusion criteria: 1.The overall age range of normal young children should be 4-11 years old, without secondary sexual characteristics. Boys: 4-11 years old; Girls: 4-8 years old; 2.The children's guardians / eligible subjects signed the informed consent form, with good compliance; 3.Daily sleep PSQI score above 10 (priority); 4.BMI index was in the standard range, and there was no weight problem; 5.Normal living habits and regular exercise; 6.Height was 1-2 standard deviations (SD) below the mean of age group; 7.The subject's current residence is limited to Shanghai; 8.Other conditions that are evaluated and confirmed by the investigator as suitable for participating in clinical experiments;
Exclusion criteria
Exclusion criteria: 1.Known etiologies such as precocious puberty, small for gestational age, achondroplasia, thyroid dysfunction, and other chronic infectious diseases; 2.Children with congenital heart, lung, kidney and liver dysfunction or severe physiological defects and developmental malformations; 3.Children with malignant tumor, genetic predisposition to familial tumor and abnormal glucose metabolism; 4.Snoring, hyperactivity disorder, anxiety disorder, autism, mental disorder and other diseases; 5.Have suffered from serious acute and chronic diseases, special physique and used growth hormone, synthetic steroids and other drugs in the past six months; 6.Children with allergic reactions to gamma aminobutyric acid foods; 7.Other situations that are not suitable for participating in clinical experiments after evaluation and confirmation by the investigator;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anthropometric indicators (height, weight, head circumference, chest circumference, waist circumference, hip circumference); | — |
Secondary
| Measure | Time frame |
|---|---|
| bone age;sleeping condition;bone mineral density; | — |
Countries
China
Contacts
Public ContactZhangqian Zheng
children's hospital of fudan university
Outcome results
None listed