Effect of ultra-fast-track cardiac anesthesia on postoperative delirium of aortic surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500097952

Enrollment

Unknown

Registered

2025-02-27

Start date

2025-03-17

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aortic disease

Interventions

ultra-fast-track anesthesia, UFTCA group:None

conventional general anesthesia, CGA group:None

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Plan for elective aortic surgery; 2. Age >=18 years old; 3.ASA grade I-III; 4.NYHA classification below Level III; 4. Preoperative awareness was clear, no cognitive dysfunction MoCA score >26 points.

Exclusion criteria

Exclusion criteria: 1. Off-pump surgery; 2. Emergency surgery; 3. Obese patients with BMI>=40kg/m2 and significant clinical manifestations of upper airway obstruction before surgery; 4. Patients with significant airway malformation or severe respiratory disease indicated by preoperative fiberoptic bronchoscopy or pulmonary CT; 5. Patients with preoperative tracheal intubation or ventilator support; 6. Patients with severe pulmonary hypertension; 7. Patients with severe heart failure, EF<30%, and unstable vital signs; 8. Suffer from severe neurological diseases, such as cerebrovascular disease, epilepsy, Parkinson's disease or Alzheimer's disease; 9. Suffering from serious mental system diseases, such as cognitive dysfunction, depression, schizophrenia, etc; 10. Special conditions occurred during the operation, such as delayed chest closure, perioperative IABP, ECMO placement, etc; 11. Patients with long-term use of psychotropic drugs or opioids before surgery; 12. Patients with a history of alcohol abuse or drug withdrawal in the past 6 months; 13. Patients who are unable to cooperate with cognitive assessment tests due to blindness, deafness, dementia, etc.

Design outcomes

Primary

Measure	Time frame
post operative delirium;	—

Secondary

Measure	Time frame
post operative cognitive dysfunction ;ICU length of stay;post operative length of stay;mortality;reintubation;reoperation;prolonged ventilation;renal failure;stroke;myocardial infarction;pneumonia ;new-onset postoperatory atrial fibrillation;infection;lactic acid;	—

Countries

China

Contacts

Public ContactLingyao Li

Beijing Anzhen Hospital, Capital Medical University

lilingyao19980404@126.com+86 150 1042 2368

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026