Postmenopausal osteoporosis
Conditions
Interventions
Experimental group:After the subjects were randomly divided into groups, they were given EuBone@ capsules, 4 capsules ×500mg/ capsule orally every day for 360 days.
Control group:After the subjects were randomly divided into groups, they were given placebo capsules, 4 capsules ×500mg/ capsule orally every day for 360 days.
Sponsors
The First Affiliated Hospital of Shandong First Medical University (Qianfoshan Hospital of Shandong Province)
Eligibility
Sex/Gender
Female
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Voluntarily sign the written informed consent, and be able to comply with the requirements and restrictions of the test; 2. Female subjects aged 45-75 years (inclusive), who have stopped menstruating for more than 12 months and have not received hormone replacement therapy; 3.Meet the standard of bone mass reduction, that is, -2.5<T value <-1.0; 4. Have the ability of independent activities;
Exclusion criteria
Exclusion criteria: 1. Abnormal lumbar vertebrae, total hip bones and femoral neck make it impossible to measure bone mineral density; 2. In patients with osteoporosis, the BMD T-score of total hip, femoral neck or lumbar spine is 400ml) in the first 3 months at random; 15.Those who have participated in interventional clinical trials of other drugs or devices within the first 3 months at random; 16. Those who suffer from primary diseases of other important organs (such as diseases of nervous system, cardiovascular system, urinary system, digestive system, respiratory system or metabolic endocrine system) and are considered unsuitable by the researcher, or those who are considered unsuitable by the researcher for other reasons; 17. Subjects that other researchers consider unsuitable to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life score;Lumbar bone mineral density; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life score;Safety index; | — |
Countries
China
Contacts
Public ContactWei Zhao/Guang Zhang
The First Affiliated Hospital of Shandong First Medical University (Qianfoshan Hospital of Shandong Province)
Outcome results
None listed