Epilepsy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed as developmental and epileptic encephalopathy (DEE); 2. Age >= 2 years, male or female; 3. Seizure frequency >=1 time per week in the past 3 months, with or without secondary seizures; 4. Patients with SEEG electrode implantation and being completed monitoring of at least 1–2 seizures. 5. Patients who agree to participate in this study and provides written informed consent after being informed of the available treatment options and potential risks.
Exclusion criteria
Exclusion criteria: 1. Patients with intracranial structural changes due to prior head surgery or traumatic brain injury, etc; 2. Patients with concomitant diseases that seriously affect their health, such as severe abnormal liver and kidney function. 3. Patients with psychiatric, cognitive, or psychological disorders, who are unable to cooperate with clinical research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| seizure rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| stereoelectroencephalographic changes; | — |
Countries
China
Contacts
The Second Affiliated Hospital of the Army Medical University