Migraine
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The patients' ages range from 18 to 70 years old. 2. According to the International Classification of Headache Disorders (ICHD-3), they meet the diagnostic criteria for either migraine with or without aura, tension-type headache, or cluster headache. 3. They can clearly describe their symptoms, answer the questionnaires, and agree to participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Medical diagnosis of chronic pain disorder; 2. Pain disorder other than chronic migraine as defined by IHS; 3. Subjects taking drugs that affect the central nervous system; 4. Subjects who have taken preventive migraine drugs within the past month; 5. Subjects with potential pathological evidence of causing headache; 6. Subjects diagnosed with arterial hypertension or with blood pressure greater than 140/90 mmHg during examination; 7. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CGRP(Calcitonin gene-related peptide);PACAP(Pituitary adenylate cyclase activating polypeptide); | — |
Countries
China
Contacts
The First Medical Center of the PLA General Hospital