Headache, dizziness, nausea, vomiting
Conditions
Interventions
DS group:After anesthesia induction, 0.9% normal saline was pumped at 4.8ml/h until the end of the operation
DC group:After anesthesia induction, cyclopofol (2.5mg/ml) was pumped at 4.8ml/h until the end of the procedure
DE group:After anesthesia induction, esketamine (2.5 mg/ml) was pumped at 4.8 ml/h until the end of the operation
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 20-80 years old; 2. ASA Class I.-III; 3. Endovascular treatment of aneurysm under general anesthesia; 4. Sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1. Diagnosed mental illness; 2. Inability to communicate due to cognitive dysfunction or language impairment before surgery; 3. Do not have the ability to read and write; 4. History of long-term sleep and anti-anxiety medication before surgery; 5. Combined with severe cardiovascular, respiratory and autonomic neuropathy; 6. Participated in clinical research of other drugs or medical devices in the past 3 months; 7) Those who cannot be enrolled in the group as determined by the investigator. 7. Those who cannot be enrolled as determined by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neurocognitive Function Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure;heart rate;Delirium;Nausea;Discomfort with indwelling catheter;Recovery time;BIS;Vomiting;Dizziness;Nightmares;Hallucinations; | — |
Countries
China
Contacts
Public ContactWang Tenghuan
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed