Asthma
Conditions
Interventions
Intervention Group:Sugammadex 0.2 mg/kg
Control Group:An equivalent volume of normal saline
Sponsors
Fourth Military Medical University Tangdu Hospital /The Second Affiliated Hospital of Air Force Military Medical University
Eligibility
Sex/Gender
All
Age
16 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of the Global Initiative for Asthma Management and Prevention (2023 updated version); 2. Have a history of asthma and be in a stable control period; 3. BMI between 18-30 kg/m^2; 4. ASA classification I to III; 5. Voluntarily sign the informed consent form; 6. Age between 16-80 years old.
Exclusion criteria
Exclusion criteria: 1. Patients with difficult airways (e.g., mouth opening degree II or above, Mallampati classification III/IV); 2. Pregnant or lactating women; 3. Patients with respiratory failure, whether receiving mechanical ventilation or not; 4. Patients with severe liver or kidney dysfunction; 5. Patients with neurological or psychiatric disorders or mental abnormalities; 6. Patients with myasthenia gravis; 7. Patients with severe cardiovascular or cerebrovascular diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Train-of-Four Ratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| The Aldrete Modified Scoring System score 20 minutes after extubation;The Aldrete Modified Scoring System score 40 minutes after extubation.;The Quality of Recovery-40 (QoR-40) score 24 hours postoperatively;The Quality of Recovery-40 (QoR-40) score 48 hours postoperatively;Neuromuscular recovery time;Extubation time;The number of adverse events occurring within 72 hours postoperatively;The number of pulmonary complications occurring within 72 hours postoperatively; | — |
Countries
China
Contacts
Public ContactChangjun Gao
Fourth Military Medical University Tangdu Hospital /The Second Affiliated Hospital of Air Force Military Medical University
Outcome results
None listed