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Deep learning and radiomics modelling based on non-constract CT applied to benign and malignant thyroid nodules, lymph node metastasis and the brafV600E mutation

Deep learning and radiomics modelling based on non-constract CT applied to benign and malignant thyroid nodules, lymph node metastasis and the brafV600E mutation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500097848
Enrollment
Unknown
Registered
2025-02-26
Start date
2024-07-01
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Papillary thyroid cancer

Interventions

Malignant thyroid nodules, lymph node metastases, BRAFV600E gene mutation group:None
Benign thyroid nodules, non-metastatic lymph nodes, BRAFV600E gene wild group:None

Sponsors

The Fourth Affiliated Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1Patients who underwent total or subtotal thyroidectomy with lymph node dissection between May 2021 and April 2024 at the Fourth Affiliated Hospital of Nanjing Medical University; 2. Postoperative pathological confirmation of papillary or follicular thyroid cancer (malignant) or nodular goiter or thyroid adenoma (benign); 3, Patients who underwent non-enhanced CT (NCCT) neck scan within 1 week before surgery.

Exclusion criteria

Exclusion criteria: 1. Patients with insufficient pathological and laboratory information; 2. Patients younger than 18 years of age; 3 Patients with obvious image artifacts that cannot be analysed.

Design outcomes

Primary

MeasureTime frame
Area under curve, AUC;Accuracy, ACC;Sensitivity, SEN;Specificity, SPE;

Secondary

MeasureTime frame
Positive predictive value, PPV;Negative predictive value, NPV;Precision, PRE;Recall, REC;F1 value;

Countries

China

Contacts

Public ContactHao Wang

The Fourth Affiliated Hospital of Nanjing Medical University

blasthao@hotmail.com+86 199 4153 2702

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 6, 2026