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Application effect of cyclopropofol in endoscopic retrograde cholangiopancreatography under nasal high-flow oxygen therapy in elderly patients

Application effect of cyclopropofol in endoscopic retrograde cholangiopancreatography under nasal high-flow oxygen therapy in elderly patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097841
Enrollment
Unknown
Registered
2025-02-26
Start date
2024-01-02
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholelithiasis leads to abdominal pain and discomfort that require ERCP treatment

Interventions

Group A:Propofol 1.2 mg/kg + alfentanil 10 ug/kg were induced, propofol 4 mg/kg/h and alfentanil 0.25-1 ug/kg/min were maintained
Group B:Cyclopofol 0.3 mg/kg + alfentanil 10 ug/kg were induced, and cyclopofol 1 mg/kg/h and alfentanil 0.25-1 ug/kg/min were maintained
Group C:Cyclopofol 0.2 mg/kg + alfentanil 10 ug/kg were induced, and cyclopofol 1 mg/kg/h and alfentanil 0.25-1 ug/kg/min were maintained

Sponsors

First Affiliated Hospital of Gannan Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.The patient is in good mental condition and communication is smooth; 2.With informed consent; 3.Age 65~85 years old; 4.No history of allergy to narcotic drugs; 5.ASA grade I - III; 6.No risk of difficult airway and aspiration.

Exclusion criteria

Exclusion criteria: 1.There are serious heart and lung diseases; 2.There are contraindications to HFNC use; 3.Emergency operation.

Design outcomes

Primary

MeasureTime frame
hemodynamics(Blood pressure);

Secondary

MeasureTime frame
Wake time;Time of onset of anesthesia;Departure time;Vital signs such as HR, MAP, SpO2 values, etc;Occurrence of intraoperative adverse events;Blood PaCO2 value;All drug usage;Doctor-patient satisfaction and 24-hour postoperative VAS score;24-hour postoperative VAS score;

Countries

China

Contacts

Public ContactHaiyu Xie

First Affiliated Hospital of Gannan Medical University

gyfyxhy@163.com+86 13576767090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026