Thoracoscopic Pulmonary Surgery
Conditions
Interventions
Group D:At the end of the operation, normal saline 2ml and ondansetron 8mg were injected intravenously.Postoperative PCIA given sufentanil 2µg/kg +normal saline to 100ml
Group G:At the end of the operation, diphenhydramine 0.2mg/kg and ondansetron 8mg were injected intravenousl.Postoperative PCIA given sufentanil 2µg/kg +diphenhydramine 0.5mg/kg+normal saline to 100ml
Sponsors
Yan 'an Hospital of Kunming City
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:1.ASA I~III level;2.Aged 18-60 years old;3.BMI18.5-33kg/m^2;4.Having signed an informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria;1. History of drug addiction,and heart, kidney, or liver failure;2.Glaucoma;3.Myasthenia gravis; 4.Patients with diphenhydramine allergy;5.Severe coagulation dysfunction; 6.Operation time > 120min; 7.The blood loss was more than 300ml
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is the quality of postoperative recovery according to the QoR-15 questionnaire scores on postoperative day 1 (POD1); | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation-agitaion scaleChoking and coughing.;NRS scale;PCA compression and rescue analgesia within 48h;The incidence and severity of postoperative nausea and vomiting (PONV);The anxiety and depression status of patients;Athens insomnia scale; | — |
Countries
China
Contacts
Public ContactJianwei YIN
Yan 'an Hospital of Kunming City
Outcome results
None listed