Myoma of uteerus
Conditions
Interventions
Experimental group
In the experimental cohort, a combination of lumbar anesthesia and non-opioid general analgesia was administered.:Experimental group: single lumbar anesthesia + intravenous infusion of midazolam 0.02-
Control group: intravenous infusion of midazolam 0.02-0.05mg/kg, Sufentanil 0.3µg/kg, propofol 2.0mg/kg, rocuronium 0.6mg/kg in fractional doses as needed, and sevoflurane inhalation anesthesia.
Control group: Opioid general analgesia:propofol 4-12mg/(kg· h), dexmedetomidine 0.2-0.7ug/(kg· h), rocuronium 0.15mg/kg in fractional doses as needed, and sevoflurane inhalation anesthesia.
Sponsors
Huaihe Hospital, Henan University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.For patients who consented to undergo elective gynecological laparoscopic total hysterectomy, the projected duration of the procedure was anticipated to be less than two hours. 2.The subjects were within the age range of 18 to 65 years, classified with ASA physical status I or II. 3.They had no known contraindications to the administration of intraspinal anesthesia. 4 were devoid of mental abnormalities that would preclude their ability to cooperate.
Exclusion criteria
Exclusion criteria: 1.The contraindications of intraspinal anesthesia include 2.Individuals with speech communication disorders who are unable to cooperate 3.Those with a history of opioid allergy or prolonged use of opioid analgesics 4.Individuals with a history of drug use 5.Patients with coagulation dysfunction 6.Body mass index>=30kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of recovery one day after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Arterial mean pressure at every time interval throughout the anesthetic period.;Patient demographic information;Surgery time;Anesthesia time;Extubation time;Sevoflurane consumption;Total hospital stay;Postoperative hospital stay;Time of first landing after surgery;Time of drainage tube removal;Time of anal exhaust;Total hospitalization expenses;Patient satisfaction;Preoperative one-day white blood cell (WBC) count;Postoperative one-day C-reactive protein (CRP) and WBC count;Pain;Adverse reactions;Cardiac rhythm measurements were recorded at each interval throughout the anesthetic period.; | — |
Countries
China
Contacts
Public ContactXin Wenqi
Huaihe Hospital of Henan University
Outcome results
None listed