generalized anxiety disorder
Conditions
Interventions
generalizes anxiety disorder group:None
health control group:None
social anxiety disorder group:None
panic disorder group:None
Sponsors
Hangzhou Seventh People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Both: Age: 18-60 years old; 2.Patients: Meet the diagnostic criteria for panic disorder according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), and are assessed as having generalized anxiety disorder, social anxiety disorder, or panic disorder through the Structured Clinical Interview for DSM-5 (SCID). Healthy subjects: Confirmed to have no history of mental or neurological disorders through screening with the Structured Clinical Interview for DSM-5 Non-Patient Edition (SCID-NP); 3.Patients: At the time of enrollment, a total score on the Hamilton Anxiety Rating Scale (HAMA-14) of >=14, and a total score on the Hamilton Depression Rating Scale (HAMD-17) of <17. Healthy subjects: At the time of enrollment, a total score on the Hamilton Anxiety Rating Scale (HAMA-14) of <7, and a total score on the Hamilton Depression Rating Scale (HAMD-17) of <7; 4.Healthy subjects: Screened using the DSM-5 Structured Clinical Interview for Non-Patient Versions (SCID-NP) to confirm no history of psychiatric or neurological disorders; 5.Healthy subjects: At enrollment, a total score of <7 on the Hamilton Anxiety Rating Scale (HAMA-14) and a total score of <7 on the Hamilton Depression Rating Scale (HAMD-17); 6.Both: Junior high school education level or above, with basic verbal expression, reading, listening, and viewing abilities, capable of understanding the scales, and able to provide verbal and written informed consent.
Exclusion criteria
Exclusion criteria: 1.Both: Currently or previously diagnosed with other mental disorders according to DSM-5 criteria, such as organic mental disorders, schizophrenia, bipolar disorder, depression, mania, substance-related and addictive disorders, etc; 2.Both: Individuals with respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), or those with severe or unstable cardiovascular, liver, kidney, hematological, endocrine, neurological, or other systemic diseases; 3.Both: Currently using medications that may affect breathing or heart rate; 4.Both: Individuals with a history of epilepsy or a family history of epilepsy; 5.Both: Patients with suicidal or self-harm ideation; 6.Both: Individuals with cognitive impairment lacking the ability to understand the study; 7.Both: Lacking the ability to use wearable devices and smartphones to complete the study; 8.Both: Pregnant or breastfeeding women; 9.Both: Patients currently undergoing biofeedback training, mindfulness, or other breathing-related psychological therapies;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| respiratory event;Time fixed EMA questionnaire;Event triggered EMA Questionnaire; | — |
Secondary
| Measure | Time frame |
|---|---|
| heart rate;heart rate variability;General condition;Chinese Big Five Personality Inventory brief version;Recent Life Events Questionnaire;Brief COPE Inventory;Respiratory symptoms questionnaire;State-Trait Anxiety Inventory;Panic Disorder Severity Scale;Beck Depression Inventory;behavioral inhibition system;Autism Spectrum Quotient;The adolescent/adult sensory profile; | — |
Countries
China
Contacts
Public ContactDeng Wei
Hangzhou Seventh People's Hospital
Outcome results
None listed