Observational Study on the Application of Magnesium Sulfate for Preventing Postoperative Sore Throat After Laryngeal Mask Airway Ventilation for Gynecological Laparoscopic Surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500097804

Enrollment

Unknown

Registered

2025-02-26

Start date

2025-03-01

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative sore throat

Interventions

NS group:Normal saline gargle before surgery

10 mg/kg group:10 mg/kg magnesium sulfate gargle before surgery

20 mg/kg group:20 mg/kg magnesium sulfate gargle before surgery

30 mg/kg group:30 mg/kg magnesium sulfate gargle before surgery

Eligibility

Sex/Gender

Female

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-60 years who underwent gynecological laparoscopic surgery under general anesthesia with laryngeal mask cannula; 2. ASA I-II.

Exclusion criteria

Exclusion criteria: 1. Preoperative chronic throat pain or/and inflammation; 2. Respiratory system diseases, such as bronchitis, bronchitis, COPD, etc.; 3. Allergic to magnesium sulfate or contraindicated; 4. Operation time less than 1 hour or more than 4 hours; 5. Suspicious and expected difficult airway.

Design outcomes

Primary

Measure	Time frame
Postoperative Sore Throat;	—

Secondary

Measure	Time frame
Hyoxemia;nausea and vomiting;Dysphagia;blood gas analysis;General information (age; Height; Weight; BMI);	—

Countries

China

Contacts

Public ContactLei Guo

General Hospital of Ningxia Medical University

czzyxgp@163.com+86 182 9518 4600

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026