Post-traumatic stress disorder
Conditions
Interventions
methylphenidate combined trauma-focused therapy group (phase 1):Traumatic-focused therapy is conducted once a week for approximately 60 minutes each time. Before each psychological treatment, take one
Traumatic-focused therapy group (phase 2):Traumatic-focused therapy is conducted once a week for approximately 60 minutes each time. Before each psychological treatment.
methylphenidate combined trauma-focused therapy group (phase 2):Traumatic-focused therapy is conducted once a week for approximately 60 minutes each time. Before each psychological treatment, take one
placebo combined trauma-focused therapy group (phase 2):Traumatic-focused therapy is conducted once a week for approximately 60 minutes each time. Before each psychological treatment, take one placebo
Sponsors
Peking University Sixth Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Adults aged 18-60 who meet all the criteria for PTSD in the CAPS-5 assessment of DSM-5. (2) CAPS-5 overall severity score 20-50. (3) The duration of symptoms is >= 6 months. (4) Have never taken psychotropic drugs, or have maintained a stable dosage of psychotropic drugs for more than 4 weeks.
Exclusion criteria
Exclusion criteria: (1) Have suffered from or currently suffer from primary psychiatric disorders, bipolar disorder, dissociative identity disorder, eating disorders with active clearance function, severe depressive disorders with psychiatric characteristics, personality disorders, severe alcohol or marijuana use disorders, and any substance use disorders within the 12 months prior to enrollment. (2) ADHD patients. (3) Organic mental disorders or neurological disorders. (4) Existence of suicidal tendencies (Colombian Suicide Scale score >= 4). (5) BMI24kg/m ². (6) Pregnant or breastfeeding. (7) Currently undergoing electroconvulsive therapy or other physical therapy. (8) Currently participating in other research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinician-administered PTSD scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton depression scale score;Hamilton anxiety scale score;clinical global impression score; | — |
Countries
China
Contacts
Public ContactYing Qian
Peking University Sixth Hospital
Outcome results
None listed