liver cirrhosis
Conditions
Interventions
Propofol Group:Propofol
Sodium Phosphopentobarbital Group:Sodium Phosphopentobarbital
Sponsors
Renmin Hospital of Wuhan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Age between 18 and 60 years old, inclusive, with no gender restrictions; 2.Diagnosed with liver cirrhosis; 3.Presence of symptoms such as hematemesis (vomiting blood), melena (black stool), anemia, or shock; 4.Alanine Aminotransferase (ALT) < 40 U/L, Aspartate Aminotransferase (AST) < 40 U/L; 5.Scheduled for gastrointestinal endoscopy or therapeutic procedures;
Exclusion criteria
Exclusion criteria: 1. Age 60 years; 2.(2) Patients with mean arterial pressure < 65 mmHg; 3.(3) Presence of malignant liver tumors; 4.(4) Presence of severe diseases in other systems, such as cardiovascular and cerebrovascular diseases: a) Cardiovascular system: New York Heart Association (NYHA) Class III or IV heart failure, Adams-Stokes syndrome; a).acute coronary syndrome (ACS) within the past 6 months; b) Patients with psychiatric disorders (such as schizophrenia, depression) and cognitive dysfunction; c) Severe renal insufficiency, patients undergoing dialysis; d) Status epilepticus, convulsions;.traumatic brain injury, intracranial hypertension, cerebral aneurysm; 5 Patients with allergies to sedative or analgesic drugs; 6 Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RASS score; | — |
Countries
China
Contacts
Public ContactLu Wang
Renmin Hospital of Wuhan University
Outcome results
None listed