coronary atherosclerotic heart disease
Conditions
Interventions
Sponsors
Jining No.1 People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Adult patients undergoing elective off-pump CABG with American Society of Anesthesiologists (ASA) class II-IV and NYHA cardiac function class II-IV.
Exclusion criteria
Exclusion criteria: 1. Serious heart disease: systolic heart failure (LVEF 120 mmHg); 3. History of severe hepatic or renal insufficiency; 4. Serious arrhythmias: resting heart rate <50 bpm, frequent premature ventricular or atrial beats, II-III° atrioventricular block, or temporary pacemakers; 5. Cognitive impairment or mental illness; 6. Known allergy to benzodiazepines or etomidate; 7. History of alcohol or drug addiction; 8. emergency surgery; 9.( other conditions that the investigator considered inappropriate for participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ?mean arterial pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| ?heart rate;Hemodynamic Indicators;cardiac output,CO;cardiac output index,CI;systemic circulation resistance,SVR;Incidence of adverse cardiovascular events during induction of anesthesia;Frequency of vasoactive drug use and cumulative dose;adverse drug event (ADE);All-cause mortality 30 days after surgery; | — |
Countries
China
Contacts
Public ContactWenzhu Wang
Jining No.1 People's Hospital
Outcome results
None listed