Colorectal cancer
Conditions
Interventions
Group C:Before operation, dexmedetomidine was continuously infused at 0.5ug/kg in group D1 and group D2, and the infusion ended within 15 min before induction, and the same amount of normal saline was
Group D1:Before operation, dexmedetomidine was continuously infused at 0.5ug/kg in group D1 and group D2, and the infusion ended within 15 min before induction, and the same amount of normal saline wa
Group D2:Before operation, dexmedetomidine was continuously infused at 0.5ug/kg in group D1 and group D2, and the infusion ended within 15 min before induction, and the same amount of normal saline wa
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age>=18 years 2. ASA classification I.-III 3. BMI between 18-25 4. Consent to surgery and sign informed consent
Exclusion criteria
Exclusion criteria: 1. Allergy to dexmedetomidine or other anesthetic drugs 2. Alcoholism or neuropsychiatric diseases 3. Long-term use of sleeping pills and sedatives 4. Opioid abuse 5. Bradyarrhythmia with baseline heart rate 800 mL) 10. Emergency reoperation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to first postoperative flatgas; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative I-FEED quality score;Time to first bowel movement;Time to first oral eating;Postoperative pain quality score;Postoperative nausea and vomiting score;Postoperative Qor-15 score;Postoperative sleep quality (AIS) score; | — |
Countries
China
Contacts
Public ContactQi Dunyi
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed