Orthostatic hypotension(OH), Orthostatic hypertension(OHT)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients admitted to the department of geriatrics inpatient and outpatient treatment, aged 18-90 years, willing to accept follow-up and observation, clear understanding, voluntary participation in the study, signed informed consent.
Exclusion criteria
Exclusion criteria: Chronic bedridden, inability to self-express, severe motor dysfunction, advanced malignancy, arrhythmias (sick sinus syndrome, high atrioventricular block, atrial flutter, atrial fibrillation, and other malignant or potentially malignant arrhythmias), severe valvular heart disease, cardiomyopathy, acute cardio-cerebrovascular disease (acute stroke and coronary heart disease events, etc.), large aneurysm or dissection Patients with pulse tumors, percutaneous transluminal coronary angioplasty or cardiac surgery, severe liver disease or hepatic insufficiency (ALT/AST or TBIL>2 times the upper limit of normal reference value), electrolyte disorders, pregnant and lactating women, a history of surgery or trauma within 1 month, and inappropriate or unable to measure carotid and femoral pulse wave data due to surgical trauma or lower limb ulcers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Supine blood pressure;Orthostatic blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Carotid-femoral pulse wave velocity;Intima-media thickness;Height;Body weight;Body mass index;Left atrial diameter;Left ventricular end-diastolic internal diameter;Inter-ventricular septum thickness;Left ventricular posterior wall thickness at end-systole;Left ventricular posterior wall depth at end-diastole;Left ventricular ejection fraction;Left ventricular end-systolic volume;Left ventricular end-diastolic volume;Triglyceride;Total cholesterol;Low density lipoprotein cholesterol;High density lipoprotein cholesterol;Total bilirubin;Direct bilirubin;Alanine aminotransferase;Aspartate aminotransferase;Gamma Glutamyl transpeptidase;Lactic dehydrogenase;Serum creatinine;Uric acid;Blood urea nitrogen;Glucose;White blood cell count;Hemoglobin;Red blood cell distribution width;Fibrinogen;Urinary albumin to creatinine ratio; | — |
Countries
China
Contacts
The First Affiliated Hospital of Fujian Medical University