Congenital heart disease
Conditions
Interventions
Intervention Group 'APRV Group':After the children in the APRV group regained spontaneous breathing, and the ventilator display showed that the diaphragm potential of the children was restored, the ve
Control Group 'PCV-VG Group':The ventilation patterns and parameters of the PCV-VG group remained unchanged until the spontaneous breathing test, and the PSV mode (PS, 6–10 cmH2O
FiO2, 40%–50%
PEEP, 4-6 cmH2O).
Sponsors
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Children postoperative period of congenital heart disease with corrective surgery(include physiological corrective surgery, eg: Fontan physiology); 2. Chest circumference>=36cm; 3.Predicting mechanical ventilation time>=48hr; 4.Recovery of spontaneous breathing within 3 hours posteroperatively; 5.Free of excessive blood loss( chest drainage <=3ml/kg/hg within the first 3 hours after the surgery); 6.Parents signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Predicting mechanical ventilation time<48hr; 2. Children underwent palliative surgery; 3. Chest circumference<36cm; 4. Severe hemodanamically unstable with/or requiring ECMO support; 5. Children with delayed chest closure; 6. Failure to recover spontaneous breathing within 3 hours posteroperatively; 7. Parents denied this study; 8. Untreated plerual effusion or pneumothorax.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of invasive mechanical ventilation;Complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of ICU stay;Duration of noninvasive mechanical ventilation; | — |
Countries
China
Contacts
Public ContactXiaolei Gong
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed