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Effects of immunosuppressive therapy on craniomaxillofacial development and oral health in children

Effects of immunosuppressive therapy on craniomaxillofacial development and oral health in children

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500097752
Enrollment
Unknown
Registered
2025-02-25
Start date
2025-03-01
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Enamel development defect

Interventions

Exposed group (Immunosuppressants are used after liver transplantation):None
Non-exposed group:None

Sponsors

Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 14 Years

Inclusion criteria

Inclusion criteria: Children aged 6-14 years (including 6 and 14 years); Well general condition ; Be able to follow up regularly as required; In mixed dentition stage.

Exclusion criteria

Exclusion criteria: Have systemic diseases other than the liver; Long-term use of drugs other than immunosuppressants; Have a history of orthodontic treatment; Parents or family history of enamel hypoplasia; History of deciduous tooth trauma and severe periapical infection; Diseases that cause high fever in infancy, such as pneumonia, diphtheria, scarlet fever, etc.; Vitamin A/D systemic nutritional deficiency, severe calcium deficiency; Grows in high fluorine area; History of craniomaxillofacial trauma.

Design outcomes

Secondary

MeasureTime frame
caries;gingiva;Oral mucosa;

Primary

MeasureTime frame
Enamel development;

Countries

China

Contacts

Public ContactBinbin Yu

Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine

yubinbinone@163.com+86 199 2150 5717

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026