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A patient-blinded, randomized controlled trial of the analgesic efficacy of low adductor block in total knee arthroplasty

A patient-blinded, randomized controlled trial of the analgesic efficacy of low adductor block in total knee arthroplasty

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097749
Enrollment
Unknown
Registered
2025-02-25
Start date
2025-03-01
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

low adductor block group:Intervention Group (Low Adductor Canal Block Group): Low adductor canal block is divided into two methods: Guided by the Tendon of the Adductor Magnus: After implant fixation

Sponsors

The first hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1 Diagnosed with knee osteoarthritis and scheduled for unilateral TKA, with no plan for contralateral TKA within the 3-month follow-up period. 2 American Society of Anesthesiologists (ASA) score of 1-3. 3 Age 18-80 years, both genders. 4 Willing and able to express consent to participate in the study. 5 Deemed by the investigator as willing and able to comply with study protocols

Exclusion criteria

Exclusion criteria: 1 Allergic to amide drugs 2 Have severe underlying diseases, including refractory hypertension, disseminated cancer, acute cerebral infarction, sequelae of cerebral hemorrhage, acute myocardial infarction, severe mental illnesses, and other comorbidities 3 Unable to tolerate general intravenous anesthesia 4 Obvious nerve damage found on the surgical side 5 Varus or valgus deformity of the knee joint on the surgical side is greater than or equal to 15 degrees 6 Intraoperative pathology suggests infection or other conditions that make joint replacement inappropriate 7 The patient has participated in other clinical research projects within the past 6 months

Design outcomes

Primary

MeasureTime frame
The cumulative pain assessed within 72 hours postoperatively using a 0-10 Numeric Rating Scale (NRS), summarized by the area under the curve;

Secondary

MeasureTime frame
the number and proportion of patients meeting discharge criteria within 24 hours postoperatively, cumulative opioid consumption within 4 hours postoperatively;the number and proportion of patients meeting discharge criteria within 24 hours postoperatively, cumulative opioid consumption within 8 hours postoperatively;the number and proportion of patients meeting discharge criteria within 24 hours postoperatively, cumulative opioid consumption within 12 hours postoperatively;the number and proportion of patients meeting discharge criteria within 24 hours postoperatively, cumulative opioid consumption within 16 hours postoperatively;the number and proportion of patients meeting discharge criteria within 24 hours postoperatively, cumulative opioid consumption within 20 hours postoperatively;the number and proportion of patients meeting discharge criteria within 24 hours postoperatively, cumulative opioid consumption within 24 hours postoperatively;

Countries

CHINA

Contacts

Public ContactQIXIN

The first hospital of Jilin University

dr.qixin@jlu.edu.cn+86 158 4307 3202

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026