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The Impact of CCR5-Positive Cells in Hematopoietic Stem Cell Grafts on Immune Reconstitution Following Transplantation in Malignant Hematological Diseases

The Impact of CCR5-Positive Cells in Hematopoietic Stem Cell Grafts on Immune Reconstitution Following Transplantation in Malignant Hematological Diseases

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500097746
Enrollment
Unknown
Registered
2025-02-25
Start date
2025-02-25
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hematologic malignancy

Interventions

Observation group:None

Sponsors

Zhongshan Hospital Affiliated to Xiamen University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.A donor for patients diagnosed with hematologic malignancies, including acute and chronic leukemia, myelodysplastic syndrome, myelofibrosis, and refractory lymphoma.

Exclusion criteria

Exclusion criteria: 1.A donor for patients diagnosed with non-malignant hematologic disease; 2.Grafts of Patients with hematologic malignancies who accept autologous hematopoietic stem cell transplantion.

Design outcomes

Primary

MeasureTime frame
Overall survial;CCR5;—

Secondary

MeasureTime frame
Progression-free Survival;Implantation rate and incidence of GVHD;—

Countries

China

Contacts

Public ContactLu Jingyuan

Zhongshan Hospital Affiliated to Xiamen University

jennylu087@sina.com+86 13599921342

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026