None
Conditions
Interventions
Gold Standard:Use the LiDCO V3 monitor to measure the patients stroke volume variation.
If the stroke volume variation is >=12%, the patient is considered to have volume responsiveness.
If the stroke
Index test:corrected flow time, FTc
respiratory variations of peak blood flow velocity, ?Vpeak
Sponsors
First Affiliated Hospital of China Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for elective abdominal surgery under general anesthesia; 2. Older than 18 years at the time of enrollment; 3. American Society of Anesthesiologists (ASA) physical status Class I-III; 4. Body mass index (BMI) between 18-31kg/m^2; 5. Patients who learn about the trial in detail and sign the informed consent voluntarily.
Exclusion criteria
Exclusion criteria: 1.Patients with carotid plaques found preoperatively or intraoperatively, and carotid ultrasound showing a stenosis degree greater than 50%; 2.Patients with preoperative comorbidities of the cardiovascular system, such as congenital heart disease, valvular disease, severe arrhythmias, or heart failure; 3.Patients with preoperative hypertension classified as stage 3, or those with a systolic blood pressure exceeding 180 mmHg and/or diastolic blood pressure exceeding 110 mmHg upon admission; 4.Patients with a history of respiratory system abnormalities or thoracic diseases, such as COPD, emphysema, asthma, rib fractures, or thoracic deformities; 5.Patients who are unable to maintain a tidal volume of 8 ml/kg mechanical ventilation for various reasons during the trial; 6.Patients who used medications that significantly affect intraoperative hemodynamics preoperatively, or have other comorbidities that may affect hemodynamics, such as hyperthyroidism or pheochromocytoma; 7.Patients who experience severe hemodynamic instability during the trial (e.g., blood pressure or heart rate fluctuations exceeding baseline values +/-20% for more than 5 minutes), or those who require vasoactive drugs during the trial; 8.Patients with a history of allergies to anesthetic drugs and intraoperative infusion fluids.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| corrected flow time, FTc;respiratory variations of peak blood flow velocity,?Vpeak;stroke volume variation,SVV; | — |
Secondary
| Measure | Time frame |
|---|---|
| general hemodynamic indicators; | — |
Countries
China
Contacts
Public ContactBao Naren
First Affiliated Hospital of China Medical University
Outcome results
None listed