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The mechanism of transcranial magnetic stimulation and functional electrical stimulation on hand function rehabilitation after stroke

The mechanism of transcranial magnetic stimulation and functional electrical stimulation on hand function rehabilitation after stroke

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097735
Enrollment
Unknown
Registered
2025-02-25
Start date
2024-08-08
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral apoplexy

Interventions

Synchronous treatment group:Simultaneous treatment of functional electrical stimulation and transcranial magnetic stimulation
Transcranial magnetic stimulation followed by functional electrical stimulation group:First transcranial magnetic stimulation, then functional electrical stimulation
Functional electrical stimulation followed by transcranial magnetic stimulation group:Functional electrical stimulation followed by transcranial magnetic stimulation
Usual care group:Basic rehabilitation

Sponsors

Huai 'an Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for stroke patients: (1) The selected stroke patients were all in line with the "Diagnostic Points of Various Cerebrovascular Diseases" revised by the Fourth National Conference on Cerebrovascular Diseases of the Chinese Medical Association, and were diagnosed with cerebral ischemia or cerebral infarction by brain CT or MRI examination; (2) Age 18-70 years old; (3) First onset, no progressive disease, motor dysfunction of one hand, affected hand ?<=Brunnstrom <=? stage; (4) Conscious and without serious cognitive impairment, the Minimental State Examination (MMSE) score was more than 17 points, which could cooperate with rehabilitation training; (5) subacute patients with stable disease within 6 months; (6) have not participated in similar studies before; (7) Agree to participate in this experiment, sign informed consent and have complete data;

Exclusion criteria

Exclusion criteria: (1) Patients who refused to be randomized; (2) Patients with severe hand dysfunction and unable to cooperate with training; (3) Patients with other serious physical diseases who cannot tolerate training; (4) Patients who could not induce MEP in the motor area of the affected side; (5) Patients with cardiac pacemakers, metal implants in the brain, cochlear implants, ventriculoperitoneal shunt, etc., who cannot be treated with transcranial magnetic stimulation; (6) Patients with local skin damage or inflammation, hyperalgesia in the stimulation area, etc., who cannot be treated with functional electrical stimulation; (7) Patients who cannot complete magnetic resonance examination; (8) Patients with sensory disorders, cognitive abnormalities, and inability to understand and cooperate with treatment and evaluation;

Design outcomes

Primary

MeasureTime frame
Regional homogeneity;Low-frequency amplitude;Ratio low-frequency amplitude;Upper limb movements;Hand movements;

Countries

China

Contacts

Public ContactLi Xuejing

Huai 'an Second People's Hospital

lixuejing914@163.com+86 139 1510 3901

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026