Kidney disease
Conditions
Interventions
Propofol group:General anesthesia was induced with propofol ( 2mg / kg ) and maintained with propofol ( initial maintenance dose of 5mg / kg / h ) combined with opioids ( remifentanil ) and cis-atracu
Cyclopophenol group:General anesthesia was induced with propofol ( 0.4 mg / kg ), and maintained with propofol ( initial maintenance dose of 0.8 mg / kg / h ) combined with opioids ( remifentanil ) an
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
35 Years to 80 Years
Inclusion criteria
Inclusion criteria: ( 1 ) Age 35-80 years old ; ( 2 ) Deviation from ideal weight <= 25 % ; ( 3 ) American Society of Anesthesiologists ASA I-III ; ( 4 ) Patients with partial nephrectomy or pyeloplasty ; ( 5 ) There was no history of long-term use of analgesic, sedative and anti-anxiety drugs ; ( 6 ) Informed consent, volunteered to participate in the trial, and signed informed consent.
Exclusion criteria
Exclusion criteria: ( 1 ) Patients refused ; ( 2 ) weight more than the ideal weight +/- 25 % ; ( 3 ) pregnancy or breastfeeding ; ( 4 ) Patients with communication disorders, cognitive dysfunction, and a history of mental illness ; ( 5 ) Allergic to propofol or propofol ; ( 6 ) patients with hereditary malignant high fever and severe renal insufficiency ; ( 7 ) Subjects who were considered unsuitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum creatinine on the first day after surgery;Creatinine clearance rate on the first postoperative day;Urine volume one hour after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative quality of life score;The decrease of mean arterial pressure during anesthesia induction;Vital sign;Use of vasoactive drugs;Incidence of adverse events; | — |
Countries
China
Contacts
Public ContactGuanghong Xu
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed