Centric fever
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Stay in the NICU > 48 hours 2. Fever: Body temperature higher than 38.3°C in at least 1 measurement in 2 consecutive days 3. Patients with no obvious downward trend in body temperature within 24 hours after conventional physical cooling and general antipyretic drugs
Exclusion criteria
Exclusion criteria: 1. Length of stay in the NICU<=48 hours 2. Fever has definite infectious factors 3. There are other non-central causes of fever, such as venous thromboembolism, blood transfusion reaction, etc 4. Fever only within 1 day
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heating duration;Daily temperature difference during fever;The time required for the thermal peak to fall below 37.3 degrees Celsius;Recurrence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Median length of ICU stay;Hospital stays;Death rate;Incidence of complications; | — |
Countries
China
Contacts
The Second Affiliated Hospital of Zhejiang University School of Medicine